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Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness
Stromal fibroblast recruitment to tumours and activation to a cancer-associated fibroblast (CAF) phenotype has been implicated in promoting primary tumour growth and progression to metastatic disease. However, the mechanisms underlying the tumour:fibroblast crosstalk that drive the intertumoural str...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4735631/ https://ncbi.nlm.nih.gov/pubmed/26777421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10305 |
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