Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis

Hypoxia-inducible factor-1α (HIF-1α) mediates hypoxic responses and regulates gene expression involved in angiogenesis, invasion and metabolism. Among the various HIF-1α posttranslational modifications, HIF-1α methylation and its physiological role have not yet been elucidated. Here we show that HIF...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Kim, Yunho, Nam, Hye Jin, Lee, Junyeop, Park, Do Young, Kim, Chan, Yu, Young Suk, Kim, Dongha, Park, Se Won, Bhin, Jinhyuk, Hwang, Daehee, Lee, Ho, Koh, Gou Young, Baek, Sung Hee
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735525/
https://ncbi.nlm.nih.gov/pubmed/26757928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10347
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы