Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates HIV‐1

Reactivation of HIV gene expression in latently infected cells together with an efficient cART has been proposed as an adjuvant therapy aimed at eliminating/decreasing the reservoir size. Results from HIV clinical trials using deacetylase inhibitors (HDACIs) question the efficiency of these latency‐...

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Dades bibliogràfiques
Publicat a:EMBO Mol Med
Autors principals: Bouchat, Sophie, Delacourt, Nadège, Kula, Anna, Darcis, Gilles, Van Driessche, Benoit, Corazza, Francis, Gatot, Jean‐Stéphane, Melard, Adeline, Vanhulle, Caroline, Kabeya, Kabamba, Pardons, Marion, Avettand‐Fenoel, Véronique, Clumeck, Nathan, De Wit, Stéphane, Rohr, Olivier, Rouzioux, Christine, Van Lint, Carine
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734845/
https://ncbi.nlm.nih.gov/pubmed/26681773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505557
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