Sequential treatment with 5‐aza‐2′‐deoxycytidine and deacetylase inhibitors reactivates HIV‐1

Reactivation of HIV gene expression in latently infected cells together with an efficient cART has been proposed as an adjuvant therapy aimed at eliminating/decreasing the reservoir size. Results from HIV clinical trials using deacetylase inhibitors (HDACIs) question the efficiency of these latency‐...

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Bibliografski detalji
Izdano u:EMBO Mol Med
Glavni autori: Bouchat, Sophie, Delacourt, Nadège, Kula, Anna, Darcis, Gilles, Van Driessche, Benoit, Corazza, Francis, Gatot, Jean‐Stéphane, Melard, Adeline, Vanhulle, Caroline, Kabeya, Kabamba, Pardons, Marion, Avettand‐Fenoel, Véronique, Clumeck, Nathan, De Wit, Stéphane, Rohr, Olivier, Rouzioux, Christine, Van Lint, Carine
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734845/
https://ncbi.nlm.nih.gov/pubmed/26681773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505557
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