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The Inference of Phased Haplotypes for the Immunoglobulin H Chain V Region Gene Loci by Analysis of VDJ Gene Rearrangements

The existence of many highly similar genes in the lymphocyte receptor gene loci makes them difficult to investigate, and the determination of phased “haplotypes” has been particularly problematic. However, V(D)J gene rearrangements provide an opportunity to infer the association of Ig genes along th...

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Publicado en:J Immunol
Main Authors: Kidd, Marie J., Chen, Zhiliang, Wang, Yan, Jackson, Katherine J., Zhang, Lyndon, Boyd, Scott D., Fire, Andrew Z., Tanaka, Mark M., Gaëta, Bruno A., Collins, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734744/
https://ncbi.nlm.nih.gov/pubmed/22205028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102097
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