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Emerging treatments in Castleman disease – a critical appraisal of siltuximab

Castleman disease (CD) is a rare, heterogeneous lymphoproliferative disorder for which no standard of care currently exists. Evidence that the pathophysiology of CD is fueled by excessive interleukin-6 (IL-6) has led to considerable interest in therapeutic targeting of this cytokine. Siltuximab, a c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biologics
Egile Nagusiak: Koff, Jean L, Lonial, Sagar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734738/
https://ncbi.nlm.nih.gov/pubmed/26869762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S60523
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