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Emerging treatments in Castleman disease – a critical appraisal of siltuximab

Castleman disease (CD) is a rare, heterogeneous lymphoproliferative disorder for which no standard of care currently exists. Evidence that the pathophysiology of CD is fueled by excessive interleukin-6 (IL-6) has led to considerable interest in therapeutic targeting of this cytokine. Siltuximab, a c...

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Detalhes bibliográficos
Publicado no:Biologics
Main Authors: Koff, Jean L, Lonial, Sagar
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734738/
https://ncbi.nlm.nih.gov/pubmed/26869762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S60523
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