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ClassTR: Classifying Within-Host Heterogeneity Based on Tandem Repeats with Application to Mycobacterium tuberculosis Infections

Genomic tools have revealed genetically diverse pathogens within some hosts. Within-host pathogen diversity, which we refer to as “complex infection”, is increasingly recognized as a determinant of treatment outcome for infections like tuberculosis. Complex infection arises through two mechanisms: w...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Chindelevitch, Leonid, Colijn, Caroline, Moodley, Prashini, Wilson, Douglas, Cohen, Ted
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734664/
https://ncbi.nlm.nih.gov/pubmed/26829497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004475
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