Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model

Even when treated with aggressive current therapies, most patients with glioblastoma survive less than two years. Rapid tumor growth, an invasive nature, and the blood-brain barrier, which limits the penetration of large molecules into the brain, all contribute to the poor tumor response associated...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ouyang, Mao, White, Ethan E., Ren, Hui, Guo, Qin, Zhang, Ian, Gao, Hang, Yanyan, Song, Chen, Xuebo, Weng, Yiming, Da Fonseca, Anna, Shah, Sunny, Manuel, Edwin R., Zhang, Leying, Vonderfecht, Steven L., Alizadeh, Darya, Berlin, Jacob M., Badie, Behnam
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734656/
https://ncbi.nlm.nih.gov/pubmed/26829221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148139
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