Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax

Tax1 encoded by the human T-cell leukemia virus type 1 (HTLV-1) has been believed to dysregulate the expression of cellular genes involved in cell survival and mortality, leading to the development of adult T-cell leukemia (ATL). The function of Tax1 in ATL development however is still controversial...

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Bibliographic Details
Published in:PLoS One
Main Authors: Mizuguchi, Mariko, Sasaki, Yuka, Hara, Toshifumi, Higuchi, Masaya, Tanaka, Yuetsu, Funato, Noriko, Tanaka, Nobuyuki, Fujii, Masahiro, Nakamura, Masataka
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734616/
https://ncbi.nlm.nih.gov/pubmed/26829041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148217
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