Synthesis of cyclic N(1)-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells

Cyclic N(1)-pentylinosine monophosphate (cpIMP), a novel simplified inosine derivative of cyclic ADP-ribose (cADPR) in which the N(1)-pentyl chain and the monophosphate group replace the northern ribose and the pyrophosphate moieties, respectively, was synthesized. The role played by the position of...

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Veröffentlicht in:Beilstein J Org Chem
Hauptverfasser: Mahal, Ahmed, D’Errico, Stefano, Borbone, Nicola, Pinto, Brunella, Secondo, Agnese, Costantino, Valeria, Tedeschi, Valentina, Oliviero, Giorgia, Piccialli, Vincenzo, Piccialli, Gennaro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Beilstein-Institut 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734301/
https://ncbi.nlm.nih.gov/pubmed/26877790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.289
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