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CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription

Spatial genome organization and its effect on transcription remains a fundamental question. We applied an advanced ChIA-PET strategy to comprehensively map higher-order chromosome folding and specific chromatin interactions mediated by CTCF and RNAPII with haplotype specificity and nucleotide resolu...

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Vydáno v:Cell
Hlavní autoři: Tang, Zhonghui, Luo, Oscar Junhong, Li, Xingwang, Zheng, Meizhen, Zhu, Jacqueline Jufen, Szalaj, Przemyslaw, Trzaskoma, Pawel, Magalska, Adriana, Wlodarczyk, Jakub, Ruszczycki, Blazej, Michalski, Paul, Piecuch, Emaly, Wang, Ping, Wang, Danjuan, Tian, Simon Zhongyuan, Penrad-Mobayed, May, Sachs, Laurent M., Ruan, Xiaoan, Wei, Chia-Lin, Liu, Edison T., Wilczynski, Grzegorz M., Plewczynski, Dariusz, Li, Guoliang, Ruan, Yijun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734140/
https://ncbi.nlm.nih.gov/pubmed/26686651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.11.024
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