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Simple horizontal magnetic tweezers for micromanipulation of single DNA molecules and DNA–protein complexes
We report the development of a simple-to-implement magnetic force transducer that can apply a wide range of piconewton (pN) scale forces on single DNA molecules and DNA–protein complexes in the horizontal plane. The resulting low-noise force-extension data enable very high-resolution detection of ch...
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| Veröffentlicht in: | Biotechniques |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4733873/ https://ncbi.nlm.nih.gov/pubmed/26757808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2144/000114369 |
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