Fetal Hemoglobin in Tunisian Sickle Cell Disease Patient: Relationship with Polymorphic Sequences Cis to the β-Globin Gene

Fetal hemoglobin (HbF) plays a dominant role in ameliorating morbidity and mortality of hemoglobinopathies. We evaluated the effects of polymorphic markers within the β-globin gene cluster to identify the genetic mechanics that influence HbF on Tunisian sickling patients (n = 242). Haplotype analysi...

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Detalhes bibliográficos
Publicado no:Indian J Hematol Blood Transfus
Main Authors: Moumni, Imen, Ben Mustapha, Maha, Ben Mansour, Ikbel, Zoraï, Amine, Douzi, Kaïs, Sassi, Sarah, Chaouachi, Dorra, Mellouli, Fethi, Bejaoui, Mohamed, Abbes, Salem
Formato: Artigo
Idioma:Inglês
Publicado em: Springer India 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733683/
https://ncbi.nlm.nih.gov/pubmed/26855518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12288-015-0504-7
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