Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle

The naturally occurring isotope of hydrogen ((1)H), deuterium ((2)H), could have an important biological role. Deuterium depleted water delays tumor progression in mice, dogs, cats and humans. Hydratase enzymes of the tricarboxylic acid (TCA) cycle control cell growth and deplete deuterium from redo...

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Gepubliceerd in:Med Hypotheses
Hoofdauteurs: Boros, László G, D’Agostino, Dominic P., Katz, Howard E., Roth, Justine P., Meuillet, Emmanuelle J., Somlyai, Gábor
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733494/
https://ncbi.nlm.nih.gov/pubmed/26826644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2015.11.016
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