pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens

Cancer immunotherapy has gained significant momentum from recent clinical successes of checkpoint blockade inhibition. Massively parallel sequence analysis suggests a connection between mutational load and response to this class of therapy. Methods to identify which tumor-specific mutant peptides (n...

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Bibliografske podrobnosti
izdano v:Genome Med
Main Authors: Hundal, Jasreet, Carreno, Beatriz M., Petti, Allegra A., Linette, Gerald P., Griffith, Obi L., Mardis, Elaine R., Griffith, Malachi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Method
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733280/
https://ncbi.nlm.nih.gov/pubmed/26825632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0264-5
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