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Copy number variants associated with 18p11.32, DCC and the promoter 1B region of APC in colorectal polyposis patients

Familial Adenomatous Polyposis (FAP) is the second most common inherited predisposition to colorectal cancer (CRC) associated with the development of hundreds to thousands of adenomas in the colon and rectum. Mutations in APC are found in ~ 80% polyposis patients with FAP. In the remaining 20% no ge...

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Detalhes bibliográficos
Publicado no:Meta Gene
Main Authors: Masson, Amy L., Talseth-Palmer, Bente A., Evans, Tiffany-Jane, McElduff, Patrick, Spigelman, Allan D., Hannan, Garry N., Scott, Rodney J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733217/
https://ncbi.nlm.nih.gov/pubmed/26909336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mgene.2015.12.005
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