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Copy number variants associated with 18p11.32, DCC and the promoter 1B region of APC in colorectal polyposis patients
Familial Adenomatous Polyposis (FAP) is the second most common inherited predisposition to colorectal cancer (CRC) associated with the development of hundreds to thousands of adenomas in the colon and rectum. Mutations in APC are found in ~ 80% polyposis patients with FAP. In the remaining 20% no ge...
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| Veröffentlicht in: | Meta Gene |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4733217/ https://ncbi.nlm.nih.gov/pubmed/26909336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mgene.2015.12.005 |
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