Detection of Rare Drug Resistance Mutations by Digital PCR in a Human Influenza A Virus Model System and Clinical Samples

Digital PCR (dPCR) is being increasingly used for the quantification of sequence variations, including single nucleotide polymorphisms (SNPs), due to its high accuracy and precision in comparison with techniques such as quantitative PCR (qPCR) and melt curve analysis. To develop and evaluate dPCR fo...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Whale, Alexandra S., Bushell, Claire A., Grant, Paul R., Cowen, Simon, Gutierrez-Aguirre, Ion, O'Sullivan, Denise M., Žel, Jana, Milavec, Mojca, Foy, Carole A., Nastouli, Eleni, Garson, Jeremy A., Huggett, Jim F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733194/
https://ncbi.nlm.nih.gov/pubmed/26659206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02611-15
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