D(3) dopamine receptor-preferring [(11)C]PHNO PET imaging in Parkinson patients with dyskinesia

OBJECTIVE: To investigate whether levodopa-induced dyskinesias (LID) are associated with D(3) overexpression in levodopa-treated humans with Parkinson disease (PD). METHODS: In this case-control study, we used PET with the D(3)-preferring radioligand [(11)C]-(+)-PHNO to estimate D(2/3) receptor bind...

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Publicat a:Neurology
Autors principals: Payer, Doris E., Guttman, Mark, Kish, Stephen J., Tong, Junchao, Adams, John R., Rusjan, Pablo, Houle, Sylvain, Furukawa, Yoshiaki, Wilson, Alan A., Boileau, Isabelle
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733157/
https://ncbi.nlm.nih.gov/pubmed/26718579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002285
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