Developmental Programming: Impact of Gestational Steroid and Metabolic Milieus on Adiposity and Insulin Sensitivity in Prenatal Testosterone-Treated Female Sheep

Prenatally testosterone (T)-treated sheep present metabolic disruptions similar to those seen in women with polycystic ovary syndrome. These females exhibit an increased ratio of small to large adipocytes, which may be the earliest event in the development of adult insulin resistance. Additionally,...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Cardoso, Rodolfo C., Veiga-Lopez, Almudena, Moeller, Jacob, Beckett, Evan, Pease, Anthony, Keller, Erica, Madrigal, Vanessa, Chazenbalk, Gregorio, Dumesic, Daniel, Padmanabhan, Vasantha
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733129/
https://ncbi.nlm.nih.gov/pubmed/26650569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1565
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