Developmental Programming: Impact of Gestational Steroid and Metabolic Milieus on Adiposity and Insulin Sensitivity in Prenatal Testosterone-Treated Female Sheep

Prenatally testosterone (T)-treated sheep present metabolic disruptions similar to those seen in women with polycystic ovary syndrome. These females exhibit an increased ratio of small to large adipocytes, which may be the earliest event in the development of adult insulin resistance. Additionally,...

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Vydáno v:Endocrinology
Hlavní autoři: Cardoso, Rodolfo C., Veiga-Lopez, Almudena, Moeller, Jacob, Beckett, Evan, Pease, Anthony, Keller, Erica, Madrigal, Vanessa, Chazenbalk, Gregorio, Dumesic, Daniel, Padmanabhan, Vasantha
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2016
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733129/
https://ncbi.nlm.nih.gov/pubmed/26650569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1565
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