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HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells
HIV encodes Tat, a small protein that facilitates viral transcription by binding an RNA structure (trans-activating RNA [TAR]) formed on nascent viral pre-messenger RNAs. Besides this well-characterized mechanism, Tat appears to modulate cellular transcription, but the target genes and molecular mec...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4733046/ https://ncbi.nlm.nih.gov/pubmed/26488441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08955 |
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