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Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cells

Dodecyl gallate (DG) is a gallic acid ester that has been shown to inhibit tumor growth. The aim of this study was to investigate the mechanism by which DG induces antiproliferative and apoptotic effects in MG-63 human osteosarcoma cells. Dose- and time-dependent cytotoxic effects of DG were determi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Med Rep
Hauptverfasser: CHENG, CHUN-HSIANG, CHENG, YEN-PO, CHANG, ING-LIN, CHEN, HSIN-YAO, WU, CHIA-CHIEH, HSIEH, CHEN-PU
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732860/
https://ncbi.nlm.nih.gov/pubmed/26707422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4717
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