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Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast
The structural diversity and biological activities of fungal indole diterpenes (IDTs) are generated in large part by the IDT cyclases (IDTCs). Identifying different IDTCs from IDT biosynthetic pathway is therefore important towards understanding how these enzymes introduce chemical diversity from a...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | J Am Chem Soc |
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Prif Awduron: | , , , , , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
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2015
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4732561/ https://ncbi.nlm.nih.gov/pubmed/26469304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b06108 |
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