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Asparaginase pharmacokinetics and implications of therapeutic drug monitoring

Asparaginase is widely used in chemotherapeutic regimens for the treatment of acute lymphoblastic leukemia (ALL) and has led to a substantial improvement in cure rates, especially in children. Optimal therapeutic effects depend on a complete and sustained depletion of serum asparagine. However, pron...

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Bibliografske podrobnosti
izdano v:Leuk Lymphoma
Main Authors: Asselin, Barbara, Rizzari, Carmelo
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732456/
https://ncbi.nlm.nih.gov/pubmed/25586605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2014.1003056
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