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Asparaginase pharmacokinetics and implications of therapeutic drug monitoring
Asparaginase is widely used in chemotherapeutic regimens for the treatment of acute lymphoblastic leukemia (ALL) and has led to a substantial improvement in cure rates, especially in children. Optimal therapeutic effects depend on a complete and sustained depletion of serum asparagine. However, pron...
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| Pubblicato in: | Leuk Lymphoma |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4732456/ https://ncbi.nlm.nih.gov/pubmed/25586605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2014.1003056 |
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