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Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins

Protease-activated receptor-1 (PAR1) is a G protein-coupled receptor that undergoes proteolytic irreversible activation by coagulant and anti-coagulant proteases. Given the irreversible activation of PAR1, signaling by the receptor is tightly regulated through desensitization and intracellular traff...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Grimsey, Neil J., Coronel, Luisa J., Cordova, Isabel Canto, Trejo, JoAnn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732206/
https://ncbi.nlm.nih.gov/pubmed/26635365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702993
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