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Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma

Multiple myeloma (MM) is characterized by an accumulation of abnormal clonal plasma cells in the bone marrow. Despite recent advancements in anti-myeloma therapies, MM remains an incurable disease. Antioxidant molecules are upregulated in many cancers, correlating with tumor proliferation, survival,...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Raninga, Prahlad V., Di Trapani, Giovanna, Vuckovic, Slavica, Tonissen, Kathryn F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732019/
https://ncbi.nlm.nih.gov/pubmed/26795735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.01.007
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