Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma

Multiple myeloma (MM) is a hematological malignancy characterized by the aberrant accumulation of clonal plasma cells in the bone marrow. Despite recent advancement in anti-myeloma treatment, MM remains an incurable disease. This study showed higher intrinsic oxidative stress and higher Trx1 and Trx...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Raninga, Prahlad V., Di Trapani, Giovanna, Vuckovic, Slavica, Bhatia, Maneet, Tonissen, Kathryn F.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558160/
https://ncbi.nlm.nih.gov/pubmed/25945832
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