Lipidomics and H(2)(18)O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos

We hypothesized that vitamin E (α-tocopherol) is required by the developing embryonic brain to prevent depletion of highly polyunsaturated fatty acids, especially docosahexaenoic acid (DHA, 22:6), the loss of which we predicted would underlie abnormal morphological and behavioral outcomes. Therefore...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: McDougall, Melissa Q., Choi, Jaewoo, Stevens, Jan F., Truong, Lisa, Tanguay, Robert L., Traber, Maret G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732018/
https://ncbi.nlm.nih.gov/pubmed/26774753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.01.004
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