The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H(2)O(2)-induced cell injury via NF-E2-related factor 2 (Nrf2) activation

Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is an important factor in the pathogenesis of age-related macular degeneration (AMD). Previous studies have shown that RTA 408, a synthetic triterpenoid compound, potently activates Nrf2. This study aimed to investigate the protec...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Liu, Xiaobin, Ward, Keith, Xavier, Christy, Jann, Jamieson, Clark, Abbot F., Pang, Iok-Hou, Wu, Hongli
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731949/
https://ncbi.nlm.nih.gov/pubmed/26773873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.12.005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados