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Allosteric Pathways in the PPARγ-RXRα nuclear receptor complex
Understanding the nature of allostery in DNA-nuclear receptor (NR) complexes is of fundamental importance for drug development since NRs regulate the transcription of a myriad of genes in humans and other metazoans. Here, we investigate allostery in the peroxisome proliferator-activated/retinoid X r...
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| Publié dans: | Sci Rep |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731802/ https://ncbi.nlm.nih.gov/pubmed/26823026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19940 |
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