Endothelin-1 Pathway Polymorphisms and Outcomes in Pulmonary Arterial Hypertension

Rationale: Pulmonary arterial hypertension (PAH) is a progressive fatal disease. Variable response and tolerability to PAH therapeutics suggests that genetic differences may influence outcomes. The endothelin pathway is central to pulmonary vascular function, and several polymorphisms and/or mutatio...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Benza, Raymond L., Gomberg-Maitland, Mardi, Demarco, Teresa, Frost, Adaani E., Torbicki, Adam, Langleben, David, Pulido, Tomas, Correa-Jaque, Priscilla, Passineau, Michael J., Wiener, Howard W., Tamari, Mayumi, Hirota, Tomomitsu, Kubo, Michiaki, Tiwari, Hemant K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731699/
https://ncbi.nlm.nih.gov/pubmed/26252367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201501-0196OC
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