Hepatic Shunting of Eggs and Pulmonary Vascular Remodeling in Bmpr2(+/−) Mice with Schistosomiasis

Rationale: Schistosomiasis is a major cause of pulmonary arterial hypertension (PAH). Mutations in the bone morphogenetic protein type-II receptor (BMPR-II) are the commonest genetic cause of PAH. Objectives: To determine whether Bmpr2(+/−) mice are more susceptible to schistosomiasis-induced pulmon...

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Publicado en:Am J Respir Crit Care Med
Main Authors: Crosby, Alexi, Soon, Elaine, Jones, Frances M., Southwood, Mark R., Haghighat, Leila, Toshner, Mark R., Raine, Tim, Horan, Ian, Yang, Peiran, Moore, Stephen, Ferrer, Elisabet, Wright, Penny, Ormiston, Mark L., White, R. James, Haight, Deborah A., Dunne, David W., Morrell, Nicholas W.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731697/
https://ncbi.nlm.nih.gov/pubmed/26308618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201412-2262OC
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