Sustained release poly (lactic-co-glycolic acid) microspheres of bone morphogenetic protein 2 plasmid/calcium phosphate to promote in vitro bone formation and in vivo ectopic osteogenesis

Bone regeneration often requires continuous stimulation to promote local bone formation. In the present study, calcium phosphate (CaPi) was used to promote transfection of human bone morphogenetic protein 2 (BMP-2) cDNA plasmid, and poly (lactic-co-glycolic acid) (PLGA) was used to prepare microsphe...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Qiao, Chunyan, Zhang, Kai, Sun, Bin, Liu, Jinzhong, Song, Jiyu, Hu, Yue, Yang, Shihui, Sun, Hongchen, Yang, Bai
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731657/
https://ncbi.nlm.nih.gov/pubmed/26885257
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