4,4′-Methylenedianiline Alters Serotonergic Transport in a Novel, Sex-Specific Model of Pulmonary Arterial Hypertension in Rats

Pulmonary arterial hypertension (PAH) is a cardiovascular disorder characterized by elevated pulmonary artery pressure as a result of arterial wall thickening. Patients are 3–4 times more likely to be women than men. This gender discrepancy demonstrates a need for an animal model with similar sex di...

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Udgivet i:Toxicol Sci
Main Authors: Carroll-Turpin, Michelle, Hebert, Valeria, Chotibut, Tanya, Wensler, Heather, Krentzel, Dallas, Varner, Kurt James, Burn, Brendan R., Chen, Yi-Fan, Abreo, Fleurette, Dugas, Tammy Renee
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Sertonergic Transport in a Model of Pulmonary Arterial Hypertension
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731411/
https://ncbi.nlm.nih.gov/pubmed/26116029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv126
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