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ROLE OF COX-2 IN THE BIOACTIVATION OF METHYLENEDIANILINE AND IN ITS PROLIFERATIVE EFFECTS IN VASCULAR SMOOTH MUSCLE CELLS

4,4′-Methylenedianiline (DAPM) is an aromatic diamine used directly in the production of polyurethane forms and epoxy resins, or as a precursor to MDI in the manufacture of some polyurethanes. In our prior experiments, we showed that chronic, intermittent treatment of female rats with DAPM resulted...

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Detalhes bibliográficos
Main Authors: Hebert, Valeria Y., Jones, Brandon Chad, Mifflin, Randy C., Dugas, Tammy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207024/
https://ncbi.nlm.nih.gov/pubmed/21720929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12012-011-9123-1
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