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Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice

See Corona and Landreth (doi:10.1093/awv300) for a scientific commentary on this article. ATP binding cassette transporter A1 (encoded by ABCA1) regulates cholesterol efflux from cells to apolipoproteins A-I and E (ApoA-I and APOE; encoded by APOA1 and APOE, respectively) and the generation of high...

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Détails bibliographiques
Publié dans:Brain
Auteurs principaux: Fitz, Nicholas F., Tapias, Victor, Cronican, Andrea A., Castranio, Emilie L., Saleem, Muzamil, Carter, Alexis Y., Lefterova, Martina, Lefterov, Iliya, Koldamova, Radosveta
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731410/
https://ncbi.nlm.nih.gov/pubmed/26510953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv293
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