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Physicochemical characterization of a ouabain isomer isolated from bovine hypothalamus.

Recent reports have shown the presence of a ouabain-like inhibitor of Na+/K(+)-ATPase in humans. We have purified a bovine hypothalamic Na+/K(+)-ATPase inhibitory factor (HIF) by using affinity chromatography combined with HPLC. This inhibitor has a molecular weight of 584 as determined by ion-spray...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Tymiak, A A, Norman, J A, Bolgar, M, DiDonato, G C, Lee, H, Parker, W L, Lo, L C, Berova, N, Nakanishi, K, Haber, E
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47314/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8396262/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.17.8189
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