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Splitting probabilities as a test of reaction coordinate choice in single-molecule experiments

To explain the observed dynamics in equilibrium single-molecule measurements of biomolecules, the experimental observable is often chosen as a putative reaction coordinate along which kinetic behavior is presumed to be governed by diffusive dynamics. Here, we invoke the splitting probability as a te...

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Detalhes bibliográficos
Publicado no:Phys Rev Lett
Main Authors: Chodera, John D., Pande, Vijay S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731355/
https://ncbi.nlm.nih.gov/pubmed/21929272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevLett.107.098102
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