T follicular helper cell-dependent clearance of a persistent virus infection requires T cell expression of the histone demethylase UTX

Epigenetic changes, including histone methylation, control T cell differentiation and memory formation, though the enzymes that mediate these processes are not clear. We show that UTX, a histone H3 lysine 27 (H3K27) demethylase, supports T follicular helper (Tfh) cell responses that are essential fo...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Immunity
Autors principals: Cook, Kevin D., Shpargel, Karl B., Starmer, Joshua, Whitfield-Larry, Fatima, Conley, Bridget, Allard, Denise E., Rager, Julia E., Fry, Rebecca C., Davenport, Marsha L., Magnuson, Terry, Whitmire, Jason K., Su, Maureen A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731234/
https://ncbi.nlm.nih.gov/pubmed/26431949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.09.002
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars