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MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus
Mesenchymal stem cell transplantation (MSCT) has been used to treat human diseases, but the detailed mechanisms underlying its success are not fully understood. Here we show that MSCT rescues bone marrow MSC (BMMSC) function and ameliorates osteopenia in Fas-deficient-MRL/lpr mice. Mechanistically,...
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| Gepubliceerd in: | Cell Metab |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731233/ https://ncbi.nlm.nih.gov/pubmed/26365178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.08.018 |
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