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Deletion of Lkb1 in Renal Tubular Epithelial Cells Leads to CKD by Altering Metabolism

Renal tubule epithelial cells are high-energy demanding polarized epithelial cells. Liver kinase B1 (LKB1) is a key regulator of polarity, proliferation, and cell metabolism in epithelial cells, but the function of LKB1 in the kidney is unclear. Our unbiased gene expression studies of human control...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Han, Seung Hyeok, Malaga-Dieguez, Laura, Chinga, Frank, Kang, Hyun Mi, Tao, Jianling, Reidy, Kimberly, Susztak, Katalin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731117/
https://ncbi.nlm.nih.gov/pubmed/26054542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121181
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