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Defective fatty acid oxidation in renal tubular epithelial cells plays a key role in kidney fibrosis development

Fibrosis is the histological manifestation of a progressive usually irreversible process causing chronic and end stage kidney disease. Genome-wide transcriptome studies of a large cohort (n=95) of normal and fibrotic human kidney tubule samples followed by systems and network analyses identified inf...

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Pubblicato in:Nat Med
Autori principali: Kang, Hyun Mi, Ahn, Seon Ho, Choi, Peter, Ko, Yi-An, Han, Seung Hyeok, Chinga, Frank, Park, Ae Seo Deok, Tao, Jianling, Sharma, Kumar, Pullman, James, Bottinger, Erwin P., Goldberg, Ira J., Susztak, Katalin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444078/
https://ncbi.nlm.nih.gov/pubmed/25419705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3762
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