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RORγt(+)Foxp3(+) Cells are an Independent Bifunctional Regulatory T Cell Lineage and Mediate Crescentic GN

Cells expressing both the regulatory T cell (Treg)-inducing transcription factor Foxp3 and the Th17 transcription factor RORγt have been identified (biTregs). It is unclear whether RORγt(+)Foxp3(+) biTregs belong to the Th17-specific Treg17 cells, represent intermediates during Treg/Th17 transdiffer...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Kluger, Malte A., Meyer, Matthias C., Nosko, Anna, Goerke, Boeren, Luig, Michael, Wegscheid, Claudia, Tiegs, Gisa, Stahl, Rolf A. K., Panzer, Ulf, Steinmetz, Oliver M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731106/
https://ncbi.nlm.nih.gov/pubmed/26054541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014090880
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