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Biasing Potential Replica Exchange Multi-Site λ-Dynamics for Efficient Free Energy Calculations

Traditional free energy calculation methods are well known for their drawbacks in scalability and speed in converging results particularly for calculations with large perturbations. In the present work, we report on the development of biasing potential replica exchange multi-site λ-dynamics (BP-REX...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Armacost, Kira A., Goh, Garrett B., Brooks, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731093/
https://ncbi.nlm.nih.gov/pubmed/26579773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct500894k
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