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Targeting the mTOR Complex by Everolimus in NRAS Mutant Neuroblastoma
High-risk neuroblastoma remains lethal in about 50% of patients despite multimodal treatment. Recent attempts to identify molecular targets for specific therapies have shown that Neuroblastoma RAS (NRAS) is significantly mutated in a small number of patients. However, few inhibitors for the potentia...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731059/ https://ncbi.nlm.nih.gov/pubmed/26821351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147682 |
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