ESR1 and ESR2 polymorphisms in the BIG 1-98 trial comparing adjuvant letrozole versus tamoxifen or their sequence for early breast cancer

PURPOSE: Estrogen receptor 1 (ESR1) and ESR2 gene polymorphisms have been associated with endocrine-mediated physiological mechanisms, and inconsistently with breast cancer risk and outcomes, bone mineral density changes and hot flushes/night sweats (HF/NS). METHODS: DNA was isolated and genotyped f...

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Udgivet i:Breast Cancer Res Treat
Main Authors: Leyland-Jones, Brian, Gray, Kathryn P., Abramovitz, Mark, Bouzyk, Mark, Young, Brandon, Long, Bradley, Kammler, Roswitha, Dell’Orto, Patrizia, Biasi, Maria Olivia, Thürlimann, Beat, Harvey, Vernon, Neven, Patrick, Arnould, Laurent, Maibach, Rudolf, Price, Karen N., Coates, Alan S., Goldhirsch, Aron, Gelber, Richard D., Pagani, Olivia, Viale, Giuseppe, Rae, James M., Regan, Meredith M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730949/
https://ncbi.nlm.nih.gov/pubmed/26590813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3634-6
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