Relative (11)C-PiB Delivery as a Proxy of Relative CBF: Quantitative Evaluation Using Single-Session (15)O-Water and (11)C-PiB PET

The primary goal of this study was to assess the suitability of (11)C-Pittsburgh compound B ((11)C-PiB) blood–brain barrier delivery (K(1)) and relative delivery (R(1)) parameters as surrogate indices of cerebral blood flow (CBF), with a secondary goal of directly examining the extent to which simpl...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Chen, Yin J., Rosario, Bedda L., Mowrey, Wenzhu, Laymon, Charles M., Lu, Xueling, Lopez, Oscar L., Klunk, William E., Lopresti, Brian J., Mathis, Chester A., Price, Julie C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730871/
https://ncbi.nlm.nih.gov/pubmed/26045309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.114.152405
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