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Influence of IgG Subclass on Human Antimannan Antibody-Mediated Resistance to Hematogenously Disseminated Candidiasis in Mice

Candida albicans is a yeast-like pathogen and can cause life-threatening systemic candidiasis. Its cell surface is enriched with mannan that is resistant to complement activation. Previously, we developed the recombinant human IgG1 antimannan antibody M1g1. M1g1 was found to promote complement activ...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Nishiya, Casey T., Boxx, Gayle M., Robison, Kerry, Itatani, Carol, Kozel, Thomas R., Zhang, Mason X.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730579/
https://ncbi.nlm.nih.gov/pubmed/26573736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00890-15
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